FIND DOCTORS
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Name: Guo,Weijian |
| Education & Professional Experience |
2008.12 Professor Fudan University Shanghai Cancer Center 2007.10 Associated professor Fudan University Shanghai Cancer Center 2006.11 Professor Shanghai Jiao Tong University 2003.1-2005.2 Post-doctor study in ENH, Northwestern University, USA 2001.11 Associated professor Shanghai Second Medical University 1994.9 - 1999.7 Ph. D. study in Shanghai Medical University, China 1989.9-1994.7 M.D. study in Zhejiang TCM University, China |
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| Specialty | Medical Oncology | |
| Research |
Cellular senescence and carcinogenesis, Basic and clinical research of GI cancer |
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| Publication |
(1) Zhang XW, Sheng YP, Li Q, Qin W, Lu YW, Cheng YF, Liu BY, Zhang FC, Li J, Dimri GP, Guo WJ. BMI1 and Mel-18 oppositely regulate carcinogenesis and progression of gastric cancer. Mol Cancer. 2010 Feb 21;9(1):40. (2)Lu YW, Li J, Guo WJ. Expression and clinicopathological significance of Mel-18 and Bmi-1 mRNA in gastric carcinoma. J Exp Clin Cancer Res. 2010 Nov 8; 29(1): 143. (3) Zhang XW, Zhang L, Qin W, Yao XH, Zheng LZ, Liu X, Li J, Guo WJ. Oncogenic role of the chromobox protein CBX7 in gastric cancer. J Exp Clin Cancer Res. 2010, 29:114. (4) Guo WJ, Datta S, Band V,Dimri GP. Mel-18, a Polycomb Group Protein Regulates Cell Proliferation and Senescence via Transcriptional Repression of Bmi-1 and c-Myc Oncoproteins. Mol Biol Cell, 2007, 18: 536-546. (5) Guo WJ, Zeng MS, Yadav A, Song LB, Guo BH, Band V, Dimri GP. Mel-18 acts as a tumor suppressor by repressing Bmi-1 expression and downregulating Akt activity in breast cancer cells. Cancer Res, 2007，67(11): 5083-9. (6) Datta S, Hoenerhoff MJ, Bommi P, Sainger R, Guo WJ, Dimri M, Band H, Band V, Green JE, Dimri GP. Bmi-1 Cooperates with H-Ras to Transform Human Mammary Epithelial Cells via Dysregulation of Multiple Growth-Regulatory Pathways. Cancer Res, 2007，67(21): 10286-95. (7) Yu Y, Chen S, Wang LS, Chen WL, Guo WJ, Yan H, Zhang WH, Peng CH, Zhang SD, Li HW, Chen GQ. Prediction of pancreatic cancer by serum biomarkers using surface-enhanced laser desorption /ionization- based decision tree classification. Oncology，2005;68(1):79-86. (8) Guo WJ, Yu EX. The Long Term Efficacy of Combined Chemoembolization and Local Irradiation in the Treatment of Patients with Large Hepatocellular Carcinoma. Hepatogastroenterol, 2003, 50: 500-503. (9) Guo WJ, Zhuang JY, Bai YR, Li J, Cheng YF, Shen Z, Li WH, Zhang WZ, Cai R. Octreotide Augments the Effects of Hepatic Arterial Occlusion in Treating a Rat Liver Tumor Model. Hepatogastroenterol, 2003, 50: 349-53. (10) Guo WJ, Li J, Ling WL, Bai YR, Zhang WZ, Cheng YF, Gu WH, Zhuang JY. Influence of hepatic arterial blockage on blood perfusion and VEGF, MMP-1 expression of implanted liver cancer in rat. World J Gastroenterology, 2002, 8(3): 476-9. (11) Guo WJ, Yu EX. Large primary liver cancer treated by chemoembolization combined with radiotherapy successfully. Hepato-Gastroenter, 2003, 50: 519-522. (12) Guo WJ, Yu EX, Liu LM, Li J, Chen Z, Lin JH, Meng ZQ, Feng Y. Comparison between chemoembolization combined with radiotherapy and chemoembolization alone for large hepatocellilar carcinoma. World J Gastroenter, 2003, 9(8):1697-1701. (13) Guo WJ, et al. Evaluation of combined therapy with chemoembolization and irradiation for large hepotocellular carcinoma. British Journal of Radiology, 2000, 73: 1091-1097. |
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| Awards | Life Science Award from Meiji Dairies | |
| Out-patient Schedule |
Monday Morning, Wednesday afternoon |
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